Research Article
A Novel Pyroptosis-Associated Gene Signature to Predict Prognosis in Patients with Colorectal Cancer
Table 1
The list of of the 12 pyroptosis-related genes.
| | Gene symbol | Description | Coefficient |
| | CASP3 | Caspase 3 | −0.2358855894 | | CHMP2A | Charged multivesicular body protein 2A | 0.1535683588 | | CHMP2B | Charged multivesicular body protein 2B | −0.5961559646 | | CHMP3 | Charged multivesicular body protein 3 | 0.0867141558 | | CHMP4C | Charged multivesicular body protein 4C | −0.0477902078 | | CHMP6 | Charged multivesicular body protein 6 | −0.1967124331 | | CHMP7 | Charged multivesicular body protein 7 | −0.2900477106 | | GSDME | Gasdermin E | 0.0820987643 | | HMGB1 | High mobility group box 1 | 0.0099448303 | | IL1A | Interleukin 1 alpha | −0.0173466610 | | IRF2 | Interferon regulatory factor 2 | 0.4575734946 | | TP63 | Tumor protein p63 | 0.0662656359 |
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Risk score = (−0.2359 CASP3) + (0.1536 CHMP2A) + (−0.5962 CHMP2B) + (0.0867 CHMP3) + (−0.0478 CHMP4C) + (−0.1967 CHMP6) + (−0.29 CHMP7) + (0.0821 GSDME) + (0.0099 HMGB1) + (−0.0173 IL1A) + (0.4576 IRF2) + (0.0663 TP63). |
