Research Article

Multitech-Based Study on Medicinal Material Basis and Action Mechanism of Herbal Formula Xian-Ling-Gu-Bao Capsule in Treatment of Osteoarthritis

Figure 7

XLGB protected ATDC5 cells against LPS-induced inflammatory response. (a) Effects of XLGB (25 μg/mL) on the expression of TNF-α, IL-1β, IL-6, and iNOS mRNAs in LPS-induced chondrocytes. (b) Effects of XLGB (25 μg/mL) on the releases of TNF-α, IL-1β, IL-6, and iNOS from LPS-induced chondrocytes. ATDC5 cells were treated with 5 μg/mL of LPS for 12 h. For drug administration, the cells were treated with XLGB extracts for 12 h before LPS stimulation. , , and compared with the control group; , , and compared with the LPS group (XLGB, Xian-Ling-Gu-Bao; LPS, lipopolysaccharide).
(a)
(b)