Research Article

Phytochemical, Cytotoxicity, and Antimycobacterial Activity Evaluation of Extracts and Compounds from the Stem Bark of Albizia coriaria Welw ex. Oliver

Table 1

Extraction yield, minimum inhibitory, and cytotoxic concentrations of the extracts of A. coriaria stem bark.

ExtractPercentage yield (%)Minimum inhibitory concentration (mg/mL)Cytotoxic concentrations (μg/mL)
M. smegmatisM. tuberculosisVero E6 cells

Hexane0.48NANA>1000a
Chloroform0.73NANA>1000a
Acetone23.01250 ± 0.0a937 ± 442a>1000a
Methanol23.21250 ± 0.0a2500 ± 0.0a>1000a
Rifampicin15 ± 0.04 ± 0.0520.02 ± 40.11

Note: a for extract vs rifampicin; NA: not active.