Phytochemical, Cytotoxicity, and Antimycobacterial Activity Evaluation of Extracts and Compounds from the Stem Bark of Albizia coriaria Welw ex. Oliver
Table 1
Extraction yield, minimum inhibitory, and cytotoxic concentrations of the extracts of A. coriaria stem bark.
Extract
Percentage yield (%)
Minimum inhibitory concentration (mg/mL)
Cytotoxic concentrations (μg/mL)
M. smegmatis
M. tuberculosis
Vero E6 cells
Hexane
0.48
NA
NA
>1000a
Chloroform
0.73
NA
NA
>1000a
Acetone
23.0
1250 ± 0.0a
937 ± 442a
>1000a
Methanol
23.2
1250 ± 0.0a
2500 ± 0.0a
>1000a
Rifampicin
—
15 ± 0.0
4 ± 0.0
520.02 ± 40.11
Note: a for extract vs rifampicin; NA: not active.