Phytochemical, Cytotoxicity, and Antimycobacterial Activity Evaluation of Extracts and Compounds from the Stem Bark of Albizia coriaria Welw ex. Oliver

Table 5

Top five docked ligands from those identified by GC-MS analysis on two protein targets.

SN	Polyketide synthase		ATP synthase
	Ligand	Binding energy (kcal/mol)	Ligand	Binding energy (kcal/mol)
1	3′,8,8′-Trimethoxy-3-piperidyl-2,2′-binaphthalene-1,1′,4,4′-tetrone (43)	−26.8626	l-Leucine, N-(2-chloroethoxycarbonyl)-N-methyl-, pentadecyl ester (27)	−28.7742
2	l-Leucine, N-(2-chloroethoxycarbonyl)-N-methyl-, pentadecyl ester (27)	−22.1684	Tetracosanoic acid, methyl ester (25)	−28.3306
3	Docosanoic acid, methyl ester (24)	−21.8569	1,2-Benzenedicarboxylic acid, butyloctyl ester (37)	−26.6023
4	Eicosanoic acid, methyl ester (22)	−21.2508	Docosanoic acid, methyl ester (24)	−25.9241
5	7-Hydroxy-3′-methoxyflavone, trimethylsilyl ether (3)	−20.1252	Eicosanoic acid, methyl ester (22)	−24.0608
6	Bedaquiline	−24.0017	Bedaquiline	−22.9042
7	Isoniazid	−10.8307	Isoniazid	−11.6257
8	Rifampicin	−17.5541	Rifampicin	−18.5886