Based on the Network Pharmacology to Investigate the Mechanism of Qingjie Fuzheng Granules against Colorectal Cancer

Table 2

The potential targets ranked by CytoNCA in the PPI network.

Rank	Betweenness		Closeness		Degree		Eigenvector		Common genes
	Genes	Score	Genes	Score	Genes	Score	Genes	Score
1	ALB	40887.94	ALB	0.546119	ALB	160	ALB	0.197964	AGT
2	IL-6	17095.32	IL-6	0.513305	IL-6	136	IL-6	0.189082	ALB
3	ESR1	10869.45	IL-1B	0.486179	AGT	89	AGT	0.162717	IL-10
4	IL-1B	9260.864	IGF1	0.483037	IGF1	88	TAC1	0.141351	IL-1B
5	DRD2	7359.653	ESR1	0.479936	IL-1B	86	SST	0.140133	DRD2
6	COL1A1	7237.071	NGF	0.473851	DRD2	83	CCL5	0.136616	IGF1
7	NGF	7171.707	AGT	0.470866	TAC1	83	DRD2	0.133437	LEP
8	IGF1	7001.154	TAC1	0.468285	ESR1	78	IL-1B	0.133364	IL-6
9	AGT	6562.12	LEP	0.467919	IL-10	78	IGF1	0.129535	TAC1
10	AR	6017.094	DRD2	0.466823	MMP9	72	CNR1	0.127909
11	TAC1	5999.071	TH	0.466095	SST	71	IL-10	0.124008
12	CALB1	5883.848	REN	0.459293	NGF	71	CCR7	0.123485
13	SHH	5830.178	CAV1	0.458589	LEP	67	BDKRB2	0.121594
14	CAV1	5809.558	AR	0.458589	CCL5	66	NMUR2	0.120083
15	LEP	5511.375	SST	0.458238	TH	65	MMP9	0.118587
16	IL10	5465.809	IL10	0.458238	F2	63	CX3CR1	0.118028
17	GPT	5407.28	CNR1	0.456837	CNR1	63	C3	0.113235
18	REN	5348.518	ACHE	0.455446	BDKRB2	60	AGTR1	0.11234
19	NOS1	5196.147	GRIN2B	0.454753	CCR7	59	PF4	0.112172
20	CYP3A4	4893.269	MMP9	0.454062	AGTR1	59	LEP	0.112127