Research Article

[Retracted] TILRR Aggravates Sepsis-Induced Acute Lung Injury by Suppressing the PI3K/Akt Pathway

Figure 4

TILRR suppresses the proliferation and induces apoptosis of HPMVECs in sepsis-induced ALI through the PI3K/Akt pathway. (a) The protein levels of Akt, p-Akt, PI3K, p-PI3K in HPMVECs treated with LPS, siTILRR, and LY294002. (b) The proliferation rate of HPMVECs treated with LPS, siTILRR, and LY294002. (c) Representative images of flow cytometric apoptosis assay in HPMVECs treated with LPS, siTILRR, and LY294002. The bar graph indicated the percentage of apoptotic cells in each group. LPS: lipopolysaccharide; siTILRR: TILRR siRNA; siNC: nontargeting siRNA; LY: LY294002. , , and .
(a)
(b)
(c)