Marsdenia tenacissima Extract Induces Autophagy and Apoptosis of Hepatocellular Cells via MIF/mToR Signaling

Figure 2

MTE induced autophagy and apoptosis of the MHCC-97H and HepG2 cells. (a) Normal morphologies of the MHCC-97H and HepG2 cells were observed using transmission electron microscopy. (b) 35 mg/mL and 50 mg/mL MTE treatment induced the formation of autophagosomes and autophagosome-lysosome structures in the MHCC-97H and HepG2 cells, respectively. (c) 35 mg/mL and 50 mg/mL MTE treatment induced the formation of apoptotic bodies in the MHCC-97H and HepG2 cells, respectively.

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