[Retracted] Application Value of Metagenomics Next-Generation Sequencing (mNGS) in Detection of Mucormycosis after Chemotherapy in Childhood Acute Leukemia

Table 1

Overview of our 7 pediatric mucormycosis cases.

Number	Age/sex	Underlying diseases	Main clinical manifestations	Specimen source/pathogenic bacteria/reads	Imaging performance	The involved organs	Antifungal drugs	Operative	Survival outcome
1	15/M	AML	Fever and cough	PB/Rhizopus mi Crosporus/(reads 125)	High-density shadow under the left lung	Lungs	LAmB posaconazole	Yes	Cure
2	11/F	ALL	Fever, cough, headache, and convulsions	PB/Rhizopus delemar/Reads 42 CSF/Rhizopus delemar/Reads 316	Cranial MRI: diffuse and abnormal enhancement on the brain surface, sulcus and brainstem margin chest CT: shadow of left lung	Lungs brain	LAmB posaconazole	No	Die
3	3/M	ALL	Fever and cough	PB/Rhizopus microsporus/reads 10 BAL/Rhizopus Microsporus/reads 10	High-density shadow in the lower lobe of both lungs	Lungs	LAmB posaconazole	No	Improved
4	1/M	ALL	Fever, cough breathe fast	BAL/Rhizomucor pusillus/reads 6	Real changes in the upper lobe of the left lung	Lungs	LAmB posaconazole	No	Improved
5	1/M	ALL	Fever, cough	BAL/Rhizomucor pusillus/Reads 3742	Double lung field multiple size unequal nodular sheet high-density shadow	Lungs	LAmB posaconazole	No	Improved
6	3/M	ALL	Fever cough	BAL/Rhizomucor pusillus/reads2 PB/Rhizomucor pusillus/reads 40	Large upper lobe of the right lung	Lungs	LAmB posaconazole	Yes	Cure
7	7/F	ALL	Fever cough	PB/Cunninghamella bertholletiae/reads 3	High-density shadow of emerging nodules in the lower lobe of the right lung	Lungs	LAmB posaconazole	No	Improved

ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; CT, computerized tomography; MRI, magnetic resonance; PB, peripheral blood; BAL, bronchoalveolar lavage fluid; CSF, cerebral spinal fluid; LAmB, liposomal amphotericin B formulation.