Research Article

Evaluation of Uterotonic Activity, Acute Oral Toxicity, and Phytochemical Composition of Uvariodendron anisatum Verdc. Root Extracts

Table 2

Summary of behavioural responses and general appearance of Wistar rats treated with single dose of U. anisatum root water extract in the acute oral toxicity study.

ObservationControl group (physiological saline)Experimental group
Single dose (300 mg/kg)Single dose (2000 mg/kg)
4 hrs24 hrs4 hrs24 hrs4 hrs24 hrs

Skin colour changeNormalNormalNormalNormalNormalNormal
Eye colour changeNormalNormalNormalNormalNormalNormal
General physiqueNo effectNo effectNo effectNo effectNo effectNo effect
DiarrhoeaUnobservedUnobservedUnobservedUnobservedUnobservedUnobserved
ComaUnobservedUnobservedUnobservedUnobservedUnobservedUnobserved
DrowsinessUnobservedUnobservedUnobservedUnobservedUnobservedUnobserved
SedationNo effectNo effectNo effectNo effectNo effectNo effect
GaspingUnobservedUnobservedUnobservedUnobservedUnobservedUnobserved
TremorUnobservedUnobservedUnobservedUnobservedUnobservedUnobserved
SalivationNormalNormalNormalNormalNormalNormal
MortalityNo deathNo deathNo deathNo deathNo deathNo death