Evaluation of Uterotonic Activity, Acute Oral Toxicity, and Phytochemical Composition of Uvariodendron anisatum Verdc. Root Extracts

Table 3

Biochemical estimation of blood serum of Wistar rats at 14th day after treatment with the U. anisatum root water extract at the 2000 mg/kg dose level in the acute oral toxicity study.

Parameter	Normal range	Mean ± SEM of observed values at 0 mg/kg (control)	Mean ± SEM of observed values at 2000 mg/kg
ALP (IU/L)	20–256	134 ± 11.12	113.5 ± 1.5
ALT (IU/L)	28–132	199 ± 6.71	102.5 ± 3.5
AST (IU/L)	59–247	183.9 ± 17.7	179.0 ± 2.0
Urea (mmol/L)	3.2–7.5	6.92 ± 3.47	7.1 ± 0.9
Creatinine (μmol/L)	4.0–57	23.13 ± 0.88	29.5 ± 0.5

n = duplicate observations, SEM: standard error of the mean.