Ukgansan Protects Dopaminergic Neurons against MPTP-Induced Neurotoxicity via the Nurr1 Signaling Pathway

<div>Summary of the experimental design. Differentiated PC12 cells and mice were treated with Ukgansan or ropinirole before MPP+ and MPTP induced the toxicity. Pole test was performed on day 3 and 7 after the last injections of MPTP. Differentiated PC12 cells were analyzed 23 h after stimulation of MPP+, and the brain tissues of mice were analyzed 7 days after the last injections of MPTP.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 7

Figure 7: Ukgansan Protects Dopaminergic Neurons against MPTP-Induced Neurotoxicity via the Nurr1 Signaling Pathway 