In Vivo Anti-Inflammatory, Analgesic, Sedative, Muscle Relaxant Activities and Molecular Docking Analysis of Phytochemicals from Euphorbia pulcherrima

Table 5

Binding energy and inhibition constant of the isolated spinacetin (1) and patuletin (2) calculated by AutoDock into the binding site of COX-2 receptors.

Compound no.	COX-2 (PDB Id: 1CX2)
	MOE	AutoDock
	BE (kcal/mol)	BE (kcal/mol)	Ki (μM)
1	−7.7702	−8.46	0.631
2	−6.8761	−7.86	1.74