Research Article
[Retracted] Inhibition of miR-29b-1-5p Attenuates Inflammatory Response and Pulmonary Fibrosis in LPS-Induced Acute Lung Injury by Regulating RTN4 Expression
Figure 1
Inhibition of miR-29b-1-5p protected MH-S cells against LPS-induced injury and inflammatory response in vitro. (a) The expression of miR-29b-1-5p in untreated MH-S cells and LPS-conditioned MH-S cells was determined using qRT-PCR. (b) The inhibition of miR-29b-1-5p in LPS-conditioned MH-S cells following the transfection of miR-29b-1-5p inhibitor was confirmed using qRT-PCR. (c) The levels of IL-1β, IL-8, TNF-α, and IL-6 in the supernatant derived from LPS-conditioned MH-S cells were measured using the ELISA method. (d) The viability of LPS-conditioned MH-S cells following the transfection of miR-29b-1-5p inhibitor was evaluated using the CCK-8 assay. (e) The apoptosis rate of LPS-conditioned MH-S cells following the transfection of miR-29b-1-5p inhibitor. , vs. MH-S cells and # vs. LPS-conditioned MH-S cells.
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