[Retracted] Inhibition of miR-29b-1-5p Attenuates Inflammatory Response and Pulmonary Fibrosis in LPS-Induced Acute Lung Injury by Regulating RTN4 Expression

Figure 4

miR-29b-1-5p mediates inflammatory response and lung injury in LPS-induced ALI in vivo through the Akt/ERK signaling pathway via the RTN4. (a) qRT-PCR and Western blot analyses of miR-29b-1-5p and RTN4 expressions in mouse lung tissues of LPS-conditioned mice. (b) W/D ratio of LPS-induced mouse lungs. (c) MPO activity of LPS-induced mouse lungs. (d) The levels of IL-1β, IL-8, TNF-α, and IL-6 in the BALF of normal mice and LPS-induced ALI mice. (e) The ratio of p-Akt/total Akt and p-ERK1/2/total ERK1/2 in lung tissues of LPS-conditioned mice. , vs. LPS-induced ALI mice and ^#vs. miR-29b-1-5p agomir.

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