Network Pharmacology Analysis and Experimental Verification Strategies Reveal the Action Mechanism of Danshen Decoction in Treating Ischemic Cardiomyopathy

Table 1

Detailed information of active ingredients of Danshen Decoction.

Hurb	Mol ID	Compound	Formula	OB (%)	DL
Salvia miltiorrhiza	MOL001601	1,2,5,6-tetrahydrotanshinone	C18H16O3	38.75	0.36
	MOL001659	Poriferasterol	C29H50O	43.83	0.76
	MOL001942	Isoimperatorin	C16H14O4	45.46	0.23
	MOL002222	Sugiol	C20H28O2	36.11	0.28
	MOL002651	Dehydrotanshinone IIA	C19H16O3	43.76	0.4
	MOL000569	Digallate	C14H9O9^-	40.12	0.26
	MOL007036	5,6-dihydroxy-7-isopropyl-1,1-dimethyl-2,3-dihydrophenanthren-4-one	C19H22O3	36.16	0.29
	MOL007041	2-isopropyl-8-methylphenanthrene-3,4-dione	C18H16O2	39.51	0.23
	MOL007045	3α-hydroxytanshinoneIIa	C19H18O4	33.77	0.44
	MOL007048	(E)-3-[2-(3,4-dihydroxyphenyl)-7-hydroxy-benzofuran-4-yl]acrylic acid	C17H12O6	40.86	0.31
	MOL007049	4-methylenemiltirone	C18H18O2	44.93	0.23
	MOL007050	2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxy-3-benzofurancarboxaldehyde	C20H20O6	48.24	0.4
	MOL007058	Formyltanshinone	C18H10O4	34.35	0.42
	MOL007059	3-beta-Hydroxymethyllenetanshiquinone	C18H14O4	62.78	0.41
	MOL007061	Methylenetanshinquinone	C18H14O3	46.69	0.36
	MOL007063	Przewalskin a	C23H30O6	73.44	0.65
	MOL007064	Przewalskin b	C20H26O4	32.16	0.44
	MOL007068	Przewaquinone B	C18H12O4	37.07	0.41
	MOL007069	Przewaquinone c	C18H16O4	37.11	0.4
	MOL007070	(6S,7R)-6,7-dihydroxy-1,6-dimethyl-8,9-dihydro-7H-naphtho[8,7-g]benzofuran-10,11-dione	C18H16O5	110.32	0.45
	MOL007071	Przewaquinone f	C18H16O5	62.24	0.46
	MOL007077	Sclareol	C20H36O2	55.74	0.21
	MOL007079	Tanshinaldehyde	C19H18O4	41.31	0.45
	MOL007081	Salvia miltiorrhizaol B	C22H26O4	40.31	0.56
	MOL007082	Salvia miltiorrhizaol A	C21H20O4	43.67	0.52
	MOL007085	Salvilenone	C20H20O2	52.47	0.38
	MOL007088	Cryptotanshinone	C19H20O3	57.95	0.4
	MOL007093	Dan-shexinkum d	C21H20O4	56.97	0.55
	MOL007094	Salvia miltiorrhizaspiroketallactone	C20H20O5	30.38	0.31
	MOL007098	Deoxyneocryptotanshinone	C19H22O3	52.34	0.29
	MOL007100	Dihydrotanshinlactone	Not found	38.88	0.32
	MOL007101	Dihydrotanshinone I	C18H14O3	50.43	0.36
	MOL007105	EpiSalvia miltiorrhizaspiroketallactone	C17H16O3	49.4	0.31
	MOL007107	C09092	C20H30O	38.68	0.25
	MOL007108	Isocryptotanshi-none	C19H20O3	45.04	0.39
	MOL007111	Isotanshinone II	C18H12O3	68.27	0.4
	MOL007115	Manool	C20H34O	36.07	0.2
	MOL007119	Miltionone I	C19H20O4	54.98	0.32
	MOL007120	Miltionone II	C19H20O4	49.92	0.44
	MOL007121	Miltipolone	C19H24O3	45.04	0.37
	MOL007122	Miltirone	C19H22O2	39.61	0.25
	MOL007124	Neocryptotanshinone II	C19H22O3	49.68	0.23
	MOL007125	Neocryptotanshinone	C19H22O4	71.03	0.32
	MOL007127	1-methyl-8,9-dihydro-7H-naphtho[5,6-g]benzofuran-6,10,11-trione	C17H12O4	36.56	0.37
	MOL007130	Prolithospermic acid	C17H14O6	38.76	0.31
	MOL007132	(2R)-3-(3,4-dihydroxyphenyl)-2-[(Z)-3-(3,4-dihydroxyphenyl)acryloyl]oxy-propionic acid	C18H16O8	44.95	0.35
	MOL007141	Salvianolic acid g	C18H12O7	39.46	0.61
	MOL007142	Salvianolic acid j	C27H22O12	52.49	0.72
	MOL007143	Salvilenone I	C20H20O2	34.72	0.23
	MOL007145	Salviolone	C18H20O2	64.37	0.24
	MOL007150	(6S)-6-hydroxy-1-methyl-6-methylol-8,9-dihydro-7H-naphtho[8,7-g]benzofuran-10,11-quinone	C18H16O5	109.38	0.46
	MOL007151	Tanshindiol B	C18H12O4	88.54	0.45
	MOL007152	Przewaquinone E	C18H16O5	45.56	0.45
	MOL007154	Tanshinone IIA	C19H18O3	43.38	0.4
	MOL007155	(6S)-6-(hydroxymethyl)-1,6-dimethyl-8,9-dihydro-7H-naphtho[8,7-g]benzofuran-10,11-dione	C19H18O4	32.43	0.45
	MOL007156	Tanshinone VI	C18H16O4	31.72	0.3
Santalum album, Salvia miltiorrhiza	MOL000006	Luteolin	C15H10O6	75.39	0.25
Santalum album	MOL000354	Isorhamnetin	C16H12O7	34.49	0.31
	MOL002322	Isovitexin	C21H20O10	42.67	0.72
Salvia miltiorrhiza, Villous amomum fruit	MOL001771	Poriferast-5-en-3beta-ol	C29H50O	49.89	0.75
Villous amomum fruit	MOL001755	24-Ethylcholest-4-en-3-one	C29H48O	42.85	0.76
	MOL001973	Sitosteryl acetate	C31H52O2	65.26	0.85
	MOL000358	β-sitosterol	C29H50O	45.64	0.75
	MOL000449	Stigmasterol	C29H48O	36.16	0.76
	MOL007514	Methyl icosa-11,14-dienoate	C21H38O2	49.6	0.23
	MOL007535	(5S,8S,9S,10R,13R,14S,17R)-17-[(1R,4R)-4-ethyl-1,5-dimethylhexyl]-10,13-dimethyl-2,4,5,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-dione	C29H48O2	31.29	0.79
	MOL007536	Stigmasta-5,22-dien-3-beta-yl acetate	C31H50O2	39.67	0.86