[Retracted] AXL Inhibits Proinflammatory Factors to Relieve Rheumatoid Arthritis Pain by Regulating the TLR4/NF-κB Signaling Pathway

Figure 2

RA model mice were induced by collagen antibodies. Lentivirus encapsulated AXL overexpression vector (oe-AXL) and negative control vector (oe-NC) were injected into the left and right ankle joints. (a) and (b) RT-qPCR and Western blot were applied to assess the level of AXL in synovial tissue of joint of RA model mice (c-e) The thickness of the rear claw and the clinical inflammation score were evaluated. (f) HE staining was used to detect the histopathological changes of knee osteoarthritis. Scale: 50 μm. (g) and (h)) Mechanical allodynia and hyperalgesia were estimated by von Frey microfilament test. , ,

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