Astragaloside IV Improves the Barrier Damage in Diabetic Glomerular Endothelial Cells Stimulated by High Glucose and High Insulin

Figure 1

GEnCs cell viability assay by MTT. (a) Astragaloside IV (AS-IV), (b) insulin (Ins), (c) high glucose (H-Glu), and (d) high glucose + high insulin (H-Glu + Ins) concentration-dependently inhibited GEnCs cell viability;  < 0.05,  < 0.01,  < 0.001 vs. control; ^# < 0.05, ^## < 0.01, ^### < 0.001 vs. H-Glu 0 mM + Ins 1 μM.

(a)

(b)

(c)

(d)