Vasorelaxant Effects of the Vitex Agnus-Castus Extract

Figure 4

Indomethacin inhibited the VACE-induced relaxant effects of rabbit aortic rings precontracted with PE. Arithmetic means ± SEM (n = 4–8 aortic rings, each from a different rabbit) of the measurements recorded in rabbit ASM with PE (0.5 µM) and treated with VACE 0.75 mg/mL without (PE + VACE) or with (after 5 min pretreatment) 10 µM indomethacin (PE + VACE + Indomethacin). Significant differences from the absence of VACE, as well as from the absence of indomethacin: , .