Analysis of Cerebrospinal Fluid Routine Biochemical Level, Pathogenic Bacteria Distribution, and Risk Factors in Patients with Secondary Intracranial Infection after Brain Tumor Surgery

Table 5

Univariate analysis of intracranial infection secondary to brain tumour surgery.

Risk factor	Infected (n = 65)		Uninfected (n = 143)		χ^2
	n	Percentage	n	Percentage
Age (years)					2.239	0.327
<35	10	15.38	35	24.47
3535∼<60	24	36.92	45	31.47
≥60	31	47.70	63	44.06
Gender					0.009	0.925
Male	35	53.85	78	54.55
Female	30	46.15	65	45.45
Tumour type					6.182	0.103
Meningioma	25	38.46	40	27.97
Glioma	23	35.39	66	46.15
Pituitary adenoma	6	9.23	23	16.09
Acoustic nerve tumour	11	16.92	14	9.79
Tumour site					15.820	<0.001
Supratentorial	32	49.23	110	76.92
Infratentorial	33	50.77	33	23.08
Operation time (h)					21.083	<0.001
<4	15	23.08	82	57.34
≥4	50	76.92	61	42.66
Postoperative indwelling drainage time					20.302	<0.001
Not put or <24 (h)	25	38.46	102	71.33
≥24	40	61.54	41	28.67
Postoperative cerebrospinal fluid leakage					17.033	<0.001
Yes	52	80.00	71	49.65
No	13	20.00	72	50.35
History of diabetes					7.608	0.006
Yes	19	29.23	19	13.29
No	46	70.77	124	86.71
History of glucocorticoid application					0.002	0.966
Yes	17	26.15	37	25.87
No	48	73.85	106	74.13
Prophylactic application of antibiotics					0.573	0.449
Yes	25	38.46	63	44.06
No	40	61.54	80	55.94