Research Article
Transcriptomic Profile Analysis of Streptococcus mutans Response to Acmella paniculata Flower Extracts
Table 1
Time-kill assessments of A. paniculata extracts against S. mutans.
| | Log10 cfu/mL | | Concentrations of extracts | 0 h | 4 h | 8 h | 24 h | 28 h |
| | Negative control | 8.75 | 8.74 | 8.67 | 8.13 | 8.01 | | APLM: 100 mg/mL | 8.75 | 0 | 0 | 0 | 0 | | APLM: 50 mg/mL | 8.75 | 6.80 | 6.49 | 5.63 | 5.93 | | APLM: 25 mg/mL (MIC) | 8.75 | 7.67 | 7.58 | 5.79 | 5.55 | | APLH: 100 mg/mL | 8.75 | 5.52 | 0 | 0 | 0 | | APLH: 50 mg/mL | 8.75 | 6.92 | 5.93 | 4.43 | 0.00 | | APLH: 25 mg/mL (MIC) | 8.75 | 7.77 | 7.62 | 6.74 | 6.46 | | APFD: 50 mg/mL | 8.75 | 6.39 | 6.09 | 0 | 0 | | APFD: 25 mg/mL | 8.75 | 6.41 | 6.04 | 5.75 | 5.19 | | APFD: 12.5 mg/mL (MIC) | 8.75 | 6.57 | 5.88 | 5.70 | 4.67 | | APFH: 50 mg/mL | 8.75 | 5.19 | 0 | 0 | 0 | | APFH: 25 mg/mL | 8.75 | 6.83 | 5.69 | 5.18 | 4.86 | | APFH: 12.5 mg/mL (MIC) | 8.75 | 6.84 | 5.90 | 5.07 | 4.99 |
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MIC values of APFH and APFD were reduced by more than 3 log10 cfu/mL of S. mutans when compared to MIC of leaf extracts (APLM and APLH).
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