Overexpression of SRD5A3 in Hepatocellular Carcinoma and Its Molecular Mechanism: A Study of Bioinformatics Exploration Analysis with Experimental Verification

Table 1

Remarkable SRD5A expression changes at transcription level between HCC cancer tissues and noncarcinoma counterparts (ONCOMINE database).

Genes	T vs. N	Fold change	value	t-test	Reference or source
SRD5A1	104 vs. 76	1.184	0.122	1.167	Chen liver [32]
	38 vs. 19	−1.012	0.529	−0.073	Mas liver [33]
	225 vs. 220	−2.460	1.000	−13.891	Roessler liver2 [34]
	22 vs. 21	−2.891	1.000	−6.954	Roessler liver [34]
SRD5A2	35 vs. 10	−9.467	1.000	−15.344	Wurmbach liver [35]
	38 vs. 19	−1.648	0.999	−3.513	Mas liver [33]
	225 vs. 220	−6.034	1.000	−28.445	Roessler liver2 [34]
	22 vs. 21	−7.017	1.000	−10.387	Roessler liver [34]
SRD5A3	104 vs. 76	1.085	0.195	0.862	Chen liver [32]
	38 vs. 19	−1.001	0.509	−0.023	Mas liver [33]
	22 vs. 21	1.008	0.393	0.273	Roessler liver [34]
	35 vs. 10	1.446	0.011	2.528	Wurmbach liver [35]
	225 vs. 220	1.036	0.032	1.862	Roessler liver2 [34]