Toxicological Evaluation of Camellia euphlebia Leaves Aqueous Extract Using Acute and Subacute Toxicity Studies in Mice and Genotoxicity Studies

Figure 4

Metaphase CHL cells exposure to various doses of CEAE or positive drugs under an optical microscope at 200× magnification: (a) vehicle control; (b) MMC (0.05 ug/mL) for 6 h treatment without S9 mixture; (c) CPA (10 ug/mL) for 6 h treatment with S9 mixture; (d) CEAE (750 ug/mL) for 6 h treatment without S9 mixture; (e) CEAE (1500 ug/mL) for 6 h treatment without S9 mixture; (f) CEAE (3000 ug/mL) for 6 h treatment without S9 mixture; (g) vehicle control; (h) MMC (0.05 ug/mL) for 24 h treatment without S9 mixture; (i) CPA (10 ug/mL) for 24 h treatment with S9 mixture; (j) CEAE (300 ug/mL) for 24 h treatment with S9 mixture; (k) CEAE (600 ug/mL) for 24 h treatment with S9 mixture; (l) CEAE (1200 ug/mL) for 24 h treatment with S9 mixture.