Ethyl Extract of Blaps rynchopetera Fairmaire Ameliorates Experimental Aerobic Vaginitis by Inhibiting Autophagy Activation
Table 2
Histopathology score of vaginal tissue in each rat group M (Q) (n = 8).
Group
Concentration (mg/kg)
Histopathology score
Mucosal lesions
Submucosal hyperemia
Inflammatory cell infiltration
Total score
Normal
0
0 (0.75)
0 (0.75)
0.50 (1.00)
1.00 (0)
Paired
0
3.00 (0.75)a
3.00 (0)a
3.00 (0)a
8.50 (1.00)a
Clindamycin
20
0.50 (1.00)b
1.00 (1.00)b
0 (0.75)b
1.50 (1.00)b
Low
100
3.00 (0.75)c
3.00 (1.00)c
3.00 (0)c
8.00 (0.75)c
Medium
200
2.00 (1.00)bc
1.50 (1.00)bc
2.00 (0)bc
5.00 (0.75)bc
High
300
0 (1.00)b
0 (1.00)bc
1.00 (0.75)bc
2.00 (1.50)bc
M (Q): median (interquartile range); acompared with the normal group, < 0.05; bcompared with the paired group, < 0.05; ccompared with the clindamycin group, < 0.05.