Zhuye Shigao Decoction Combined with Qingqi Huatan Pills in Alleviating the Acute Exacerbation of Chronic Obstructive Pulmonary Disease (Phlegm-Heat Stagnating in the Lungs) via the IL-6-Mediated JAK1/STAT3 Signaling Pathway

Figure 5

SOCS3 expression is upregulated in lung tissue. (a) Western blot analysis of SOCS3 in lung tissue, β-actin was used as the internal reference. (b) The photomicrographs of immunohistochemical staining for SOCS3 among lung tissue samples are displayed. The nucleus is colored in blue and the positive cells are colored in brown (scale bar is 50 µm, ×400). (c) Semiquantitative analysis on the basis of the intensity of protein bands in eight groups. (d) The relative SOCS3 gene expression. Error bars represent SD, n = 3. , ^#, ^&, ^Δ represent values <0.05 which are considered statistically significant. versus MC (model control), ^# versus herbs low, ^& versus herbs mid, and ^Δ versus herbs high.

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