Huangjia Ruangan Granule Inhibits Inflammation in a Rat Model with Liver Fibrosis by Regulating TNF/MAPK and NF-κB Signaling Pathways

Figure 3

HJRG can reduce the progression of fibrosis. (a) Sirius red staining of liver tissue sections (magnification, 40X and 100X). (b) Quantification of collagen deposition by Sirius red staining (n = 3). (c) Four serum indexes of liver fibrosis: PC III, Col IV, LN, and HA (n = 12). (d) HYP contents in liver tissue (n = 8). (e) Effects of HJRG on protein levels of α-SMA, desmin, and vimentin in liver tissue. (f) Quantification of α-SMA, desmin, vimentin, and the protein expression in liver tissue (n = 5). and , compared with the control group; and , compared with the model group. Control: control group; Model: model group; silymarin: silymarin group; HJRG-L: Huangjia Ruangan granule low-dose group; HJRG-M: Huangjia Ruangan granule medium-dose group; HJRG-H: Huangjia Ruangan granule high-dose group.

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