Huangjia Ruangan Granule Inhibits Inflammation in a Rat Model with Liver Fibrosis by Regulating TNF/MAPK and NF-κB Signaling Pathways

Figure 4

Analysis of network pharmacology related to HJRG. (a) The flower plot of the active ingredients in HJRG. The pink circle in the center represents the 117 active ingredients of HJRG. Each petal corresponds to the number of compounds in the corresponding Chinese medicine. (b) The flower plot of the potential target in HJRG. The pink circle in the center represents the 261 potential targets of HJRG. Each petal corresponds to the number of potential targets in the corresponding Chinese medicine. (c) A Venn diagram showing that HJRG shares 219 potential targets with the targets of liver fibrosis. (d) The component-target network. (e) PPI network analysis of potential targets. (f) Top 10 items of BP, CC, and MF in the GO enrichment analysis of potential targets. BP: biological process; CC: cellular component; MF: molecular function. (g) Top 15 items of the KEGG pathway analysis of the potential targets.

(a)

(b)

(c)

(d)

(e)

(f)

(g)