Molecular Mechanism Investigation on Monomer Kaempferol of the Traditional Medicine Dingqing Tablet in Promoting Apoptosis of Acute Myeloid Leukemia HL-60 Cells

Figure 1

Analysis of the regulatory network of Dingqing tablets-key components-targets-acute myeloid leukemia based on network pharmacology. (a) Venn diagram of overlapped genes between Dingqing Tablet and human AML targets. (b) Venn diagrams of overlapped genes between Radix Notoginseng, Citrus Reticulata, Codonopsis, Cortex Moutan, Indigo Naturalis, and Eolite and human AML targets. (c) Protein-protein interaction analysis of 92 proteins. (d) Drug-active ingredient-target gene network diagram. DQP represented the compound drug Dingqing Tablet, and SSQ, CP, DS, MDP, QD, and XH, respectively, represented the six herbs containing in Dingqing Tablet: Radix Notoginseng, Citrus Reticulata, Codonopsis, Cortex Moutan, Indigo Naturalis, and Eolite.

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