Molecular Mechanism Investigation on Monomer Kaempferol of the Traditional Medicine Dingqing Tablet in Promoting Apoptosis of Acute Myeloid Leukemia HL-60 Cells

Figure 4

Kaempferol inhibits HL-60 cell proliferation. (a) HL-60 cell growth curves. HL-60 cells were treated with kaempferol (25 μM, 50 μM, and 100 μM) and ATRA (10 μM) for 72 h (b, c) Representative images (b) and quantification (c) were obtained via EdU incorporation assays. HL-60 cells were treated with kaempferol (25 μM, 50 μM, and 100 μM) and ATRA (10 μM) for 48 h. Data were represented as mean ± SD (n ≥ 3). , , , as determined using Student’s t-test for pairwise comparison or one-way ANOVA, followed by Tukey’s test for multiple group comparison.

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