Research Article
Ta-Xi-San Suppresses Atopic Dermatitis Involved in Multitarget Mechanism Using Experimental and Network Pharmacology Analysis
Table 3
The pharmacodynamic targets of TXS for AD.
| No. | Target | Betweenness centrality (BC) | Closeness centrality (CC) | Degree |
| 1 | PTGS2 | 0.12968939 | 0.48461538 | 41 | 2 | PTGS1 | 0.03576985 | 0.38729508 | 27 | 3 | HSP90AA1 | 0.02247622 | 0.36914063 | 21 | 4 | ESR1 | 0.0193549 | 0.38259109 | 15 | 5 | PRKACA | 0.00849434 | 0.34615385 | 14 | 6 | RXRA | 0.00732045 | 0.32926829 | 14 | 7 | NOS2 | 0.01528486 | 0.37951807 | 12 | 8 | ADRB2 | 0.00526221 | 0.32363014 | 11 | 9 | TNF | 0.03753438 | 0.42376682 | 11 | 10 | TOP2A | 0.00637523 | 0.33392226 | 11 |
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