Optimization and Evaluation of the Quercus infectoria Galls Thermosensitive In Situ Gel for Rectal Delivery

Table 2

Results of Box-Behnken design response surface methodology ( ± S, n = 3).

Run	X1 (%)	X2 (%)	X3 (%)	Experimental Tsol-gel (°C)
1	+1	0	+1	29.5 ± 0.1
2	0	0	0	31.4 ± 0.5
3	0	0	0	31.7 ± 0.2
4	0	+1	−1	32.5 ± 0.3
5	−1	−1	0	33.2 ± 0.4
6	0	0	0	31.7 ± 0.4
7	−1	0	+1	35.3 ± 0.5
8	+1	+1	0	30.2 ± 0.2
9	−1	+1	0	36.2 ± 0.4
10	0	+1	+1	34.1 ± 0.3
11	−1	0	−1	34.3 ± 0.2
12	+1	−1	0	27.2 ± 0.4
13	0	−1	−1	29.5 ± 0.2
14	0	−1	+1	31.3 ± 0.4
15	0	0	0	32.2 ± 0.1
16	0	0	0	30.9 ± 0.3
17	+1	0	−1	28.1 ± 0.2