Treatment of Modified Dahuang Fuzi Decoction on Cognitive Impairment Induced by Chronic Kidney Disease through Regulating AhR/NF-κB/JNK Signal Pathway

Figure 9

Related mRNA expression levels in the mice brain and kidney of all groups. (a–c) AhR, NF-κB, and JNK mRNA expression levels in the mice kidney. (d–h) AhR, NF-κB, JNK, BDNF, and TrkB mRNA expression levels in the mice brain (, comparable to the S group; , comparable to the M group; , comparable to the M group; S, sham operation group; M, model group; P, positive control group; MDFD-H, modified Dahuang Fuzi Decoction high-dose group; MDFD-M, modified Dahuang Fuzi Decoction medium-dose group; MDFD-L, modified Dahuang Fuzi Decoction low-dose group; AhR, aryl hydrocarbon receptor; BDNF, brain-derived neurotrophic factor; TrkB, tropomyosin receptor kinase B; NF-κB, nuclear factor-κB; JNK, c-Jun N-terminal kinase).

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