Research Article
Xiaoyao-Qingluoyin Cure Adjuvant-Induced Arthritis by Easing LPS Response-Related Pathway-Mediated Immune Abnormality
Figure 1
Therapeutic effects of QLY and XYQLY treatments on AIA rats. (a) Periodic arthritic score changes; (b) morphological observation of hind paws (yellow arrow, local swelling and edema); (c) DR examination of left hind paw (yellow arrow, joint cavity narrowing); (d) histological examination of interphalangeal joints of left hind paw (yellow arrow, cartilage erosion); (e) local expression of MMP3 in cartilage (investigated by immunohistochemical method; yellow arrow, chondrocytes highly expressing MMP3); (f) levels of SOD, GSH, MDA, T-AOC, and NO in serum; (g) results of CBC; and (h) levels of TNF-α and CO in serum. Statistical significance: and compared with AIA models.