Xiaoyao-Qingluoyin Cure Adjuvant-Induced Arthritis by Easing LPS Response-Related Pathway-Mediated Immune Abnormality

Figure 3

Identification of therapeutic targets and related chemicals of the formulas. (a) GO pathway enrichment analysis based on reported targets of chemicals derived from QLY and XYQLY; (b) the interactions among chemicals and LPS response-related genes; and (c) LPS signaling-related compounds within the formulas detected by LC-MS analysis. The 4 subfigures represent compounds closely related to the regulation of the LPS signaling pathway, namely, formononetin, benzoylpaeoniflorin, paeoniflorin, and paeoniflorin. Red arrows indicate compounds closely related to the regulation of LPS.

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