Renoprotective and Cardioprotective Potential of Moricandia sinaica (Boiss.) against Carbon Tetrachloride-Induced Toxicity in Rats

Table 2

Effect of extracts on kidney function test treated with CCl₄.

Treatments	Dose (mg/kg)	Creatinine (mg/dl)		Uric acid (mg/dl)
		Mean ± S.E	(%) change	Mean ± S.E	(%) change
Normal		1.45 ± 0.03		1.26 ± 0.08
CCl4		4.10 ± 0.08	181↑	4.45 ± 0.21	253↑
Silymarin + CCl4	10	1.87 ± 0.10	54↓	1.83 ± 0.08	59↓
MOR-1 + CCl4	100	3.81 ± 0.14	7↓	4.59 ± 0.015	3↓
MOR-1 + CCl4	200	3.09 ± 0.07	25↓	4.26 ± 0.11	4↓
MOR-2 + CCl4	100	2.46 ± 0.05	40↓	3.14 ± 0.19	29↓
MOR-2 + CCl4	200	2.05 ± 0.04	50↓	2.40 ± 0.11	46↓
MOR-3 + CCl4	100	3.80 ± 0.11	7↓	4.50 ± 0.21
MOR-3 + CCl4	200	3.12 ± 0.06	24↓	4.78 ± 0.17	7↑

All values represent mean ± SEM. ; ; ANOVA, followed by the Dunnett’s multiple comparison test. 1- CCl₄ group compared to the normal group, 2-Treated groups compared with the CCl₄ group. It is quantity level of doses in (mg/kg).