Tetrandrine Ameliorates Rheumatoid Arthritis in Mice by Alleviating Neutrophil Activities

Figure 1

The effect of TET on the AA mouse model. AA mice were injected with PBS, TET, and DEX intraperitoneally every day. The joint data were acquired every three days. The sera were acquired after sacrifice. (a) The schematic diagram of the mice experiment. AA inflammation was induced on Day 0, and the drugs were given beginning on Day 3. (b) Representative images of the paws of the mice. The limbs that were injected with PBS or FCA are marked by the red rectangle. (c) The arthritic score of the AA mice. (d) The ankle joint diameter of the mice. (e) The concentration of IFN-γ in each group. (f) The concentration of IL-6 in each group. (g) The concentration of TNF-α in each group. For each group, n ≥ 5, the bars are represented by the mean ± SD compared with the control group. compared with the AA group. compared with the AA group. Ns, , the difference was statistically nonsignificant.

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