Tetrandrine Ameliorates Rheumatoid Arthritis in Mice by Alleviating Neutrophil Activities

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Markers</td><td class="align_center">Control</td><td class="align_center">LPS</td><td class="align_center">LPS + TET 10 <i>μ</i>Μ</td><td class="align_center">LPS + TET 20 <i>μ</i>Μ</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">TNF-<i>α</i></td><td class="align_center">1.000 ± 0.000</td><td class="align_center">8.7531 ± 2.508</td><td class="align_center">11.07 ± 1.280</td><td class="align_center">11.89 ± 1.333</td></tr><tr><td class="align_left">IFN-<i>γ</i></td><td class="align_center">1.000 ± 0.000</td><td class="align_center">2.367 ± 0.810</td><td class="align_center">1.943 ± 0.534</td><td class="align_center">4.473 ± 0.669</td></tr><tr><td class="align_left">IL-1<i>β</i></td><td class="align_center">1.000 ± 0.000</td><td class="align_center">7.513 ± 1.113</td><td class="align_center">2.893 ± 0.573</td><td class="align_center">2.540 ± 0.292</td></tr><tr><td class="align_left">IL-6</td><td class="align_center">1.000 ± 0.000</td><td class="align_center">58.000 ± 13.000</td><td class="align_center">7.890 ± 2.790</td><td class="align_center">17.050 ± 3.388</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>The results are presented as mean ± SD. The control group was set to 1.000 ± 0.000.<br/></div></td></tr></table>

<div>TET reduced the mRNA levels of IL-1<i>β</i> and IL-6.</div>

Evidence-Based Complementary and Alternative Medicine

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Table 3

Table 3: Tetrandrine Ameliorates Rheumatoid Arthritis in Mice by Alleviating Neutrophil Activities 