Research Article
Hydroalcoholic Extract of Sechium edule Fruits Attenuates QT Prolongation in High Fat Diet-Induced Hyperlipidemic Mice
Table 1
Effect of S.E. extract on lipid profile in HFD-induced hyperlipidemic mice.
| Treatment | Total cholesterol (mg/dl) | Triglycerides (mg/dl) | HDL-C (mg/dl) | LDL-C (mg/dl) | VLDL-C (mg/dl) |
| Normal control | 75.03 ± 1.18 | 73.63 ± 1.544 | 37.82 ± 1.01 | 22.48 ± 0.84 | 14.72 ± 0.31 | HFD control | 200.47 ± 3.52 | 137.30 ± 3.02 | 21.70 ± 0.82 | 148.54 ± 3.03 | 27.45 ± 0.60 | HFD + atorvastatin (10 mg/kg) | 97.90 ± 2.50 | 85.82 ± 1.50 | 34.18 ± 0.67 | 46.55 ± 3.18 | 17.165 ± 0.30 | HFD + S.E. extract (200 mg/kg) | 103.98 ± 1.04 | 102.72 ± 1.04 | 29.22 ± 0.68 | 55.09 ± 0.97 | 20.599 ± 0.18 | HFD + S.E. extract (400 mg/kg) | 92.35 ± 2.46 | 82.55 ± 0.83 | 31.392 ± 0.43 | 44.44 ± 2.56 | 16.437 ± 0.18 |
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n = 6, data are expressed in Mean ± SEM. , HDF control vs. normal control. , treatment groups vs. HDF control. |