Network Pharmacology and Experimental Verification Revealed the Mechanism of Yiqi Jianpi Recipe on Chronic Obstructive Pulmonary Disease

Figure 1

Experimental scheme diagram. In the model establishment group, 200 ug LPS was gradually instilled into the airway on days 1 and 14. These rats were not exposed to smoke on the day of instilled LPS, but were exposed to smoke for 12 weeks. From Week 9 onward, continuous drug intervention for 12 weeks was conducted and all rats (including the control group) were sacrificed and the samples were obtained at the end of week 20.