Research Article

Network Pharmacology Analyses of the Pharmacological Targets and Therapeutic Mechanisms of Salvianolic Acid A in Myocardial Infarction

Table 2

Potential molecular targets of salvianolic acid A by the SwissTargetPrediction web tool.

TargetTarget ClassTargetTarget Class

CA12LyaseAURKAKinase
CA4LyaseAKR1B10Enzyme
CA7LyaseDHFROxidoreductase
CA2LyaseF3 F7Protease
MMP1ProteaseCASP1Protease
AKR1B1EnzymeAGTR1Family A G protein-coupled receptor
FYNKinaseHMGCROxidoreductase
TTRSecreted proteinTHRBNuclear receptor
MMP9ProteaseITGB5 ITGAVMembrane receptor
MMP12ProteaseIMPDH1Oxidoreductase
MMEProteaseERBB2Kinase
SLC28A2Electrochemical transporterLCKKinase
ADAMTS4ProteaseHSP90AB1Other cytosolic protein
ADORA3Family A G protein-coupled receptorLDHAEnzyme
ACEProteaseTHRANuclear receptor
SLC5A1Electrochemical transporterMMP8Protease
GRM2Family C G protein-coupled receptorECE1Protease
ITGB7 ITGA4Membrane receptorPTGDR2Family A G protein-coupled receptor
F7ProteaseCA14Lyase
ALBSecreted proteinDHODHOxidoreductase
MMP2ProteaseTDP1Enzyme
PIM1KinaseGALK1Enzyme
SELPAdhesionABL1Kinase
MMP13ProteasePADI1Enzyme
SELLAdhesionMAP3K9Kinase
IGFBP3Secreted proteinF3Surface antigen
KDM4CEraserMMP10Protease
SLC5A2Electrochemical transporterPADI4Enzyme
MMP3ProteaseAMPD3Enzyme
SELEAdhesionITGA2B ITGB3Membrane receptor
ITGB1 ITGA4Membrane receptorC3AR1Family A G protein-coupled receptor
HCAR2Family A G protein-coupled receptorTYROxidoreductase
CA1LyaseADKEnzyme
TYMSTransferaseAMPD2Enzyme
SLC6A2Electrochemical transporterEGFRKinase
AKR1C2EnzymeYARSEnzyme
APPMembrane receptorITGAV ITGB3Membrane receptor
ITGAV ITGB1Membrane receptorSLC5A4Electrochemical transporter
MAPK8KinaseSRD5A1Oxidoreductase
ROCK2KinasePADI2Enzyme
GARTLigasePADI3Enzyme
PRKCAKinaseEPHA2Kinase
CASP3ProteaseFGFR1Kinase
F10ProteaseLDHBEnzyme
CA9LyaseBTKKinase
SRCKinaseSLC28A3Electrochemical transporter
KDRKinaseCA5ALyase
SLC29A1Electrochemical transporterCA6Lyase
ESR1Nuclear receptorCA5BLyase
ACE2ProteaseCA13Lyase