Mechanistic Insights of Qingre Jiedu Recipe Based on Network Pharmacology Approach against Heart Failure

Figure 6

Effects of QJ on PI3K-AKT signaling pathway. (a) QJ (200, 400, 800, and 1000 mg/mL) has no toxicity on the H9C2 cells and increases cell viability remarkably in the H₂O₂-stimulated H9C2 model. (b) (c) The production of ROS on H₂O₂-stimulated H9C2 cells. (d) Western blotting detected the expressions of p-AKT in H9C2 cells. Data were presented as the mean ± standard error of three independent experiments (N = 3 per group for WB and N = 6 per group for the other experiments; ).

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