Curcumin Regulates Gut Microbiota and Exerts a Neuroprotective Effect in the MPTP Model of Parkinson’s Disease

Figure 4

Analysis of 16SrRNA in the gut microbiota of PD mice shows that curcumin regulates the dysregulation of gut microbiota in PD mice. (a) Alpha diversity of gut microbiota based on chao-1. (b) Dilution curves based on the Simpson index. (c) Beta diversity based on PCA analysis. Various colors represent samples of mice from different groups, and the closer the distance between two spots, the smaller the disparity in community composition between the two. (d) Stacked bar graph of relative abundance of gut microbiota at the phylum level. (e) Stacked bar graph of relative abundance of gut microbiota at the family level. (f) A heatmap analysis at the family level. (g) The Venn diagram. Only the top 30 species with the highest relative abundance are shown, and the remaining species are classified as others.

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