Research Article

[Retracted] Muscone Inhibits the Excessive Inflammatory Response in Myocardial Infarction by Targeting TREM-1

Figure 6

Muscone inhibits the production of DAMP-triggered (damage-associated molecular pattern trigger) inflammatory cytokines. In addition, muscone inhibits the signal activation of p38 and NF-κB under DAMP-induced conditions (a). Muscone inhibits rmHMGB1 (1 μg/ml)-induced increase in cytoinflammatory factors in the supernatant of macrophages. (b). Muscone inhibits rmHSP60 (1 mol/ml)-induced increase in cytoinflammatory factors in the supernatant of macrophages. (c). Western blot was used to detect the expression in the p-p38, p-p65 and p-JNK expression in each group after different treatments. (d). Statistical results of p-p38, p-p65 and p-JNK expressions in each group after different treatments. .
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