Research Article

Network Pharmacology-Based Analysis of the Potential Biological Mechanisms of Coix Seed against Colorectal Cancer

Table 2

Target genes related to the active compounds in coix seeds.

CompoundTarget gene

SitosterolPGR, NCOA2, NR3C2
StigmasterolPGR, NR3C2, NCOA2, ADH1C, IGHG1, RXRA, NCOA1, PTGS1, PTGS2, ADRA2A, SLC6A2, SLC6A3, ADRB2, AKR1B1, PLAU, LTA4H, MAOB, MAOA, PRKACA, CTRB1, CHRM3, CHRM1, ADRB1, SCN5A, HTR2A, ADRA1A, GABRA3, CHRM2, ADRA1B, GABRA1, CHRNA7
CLRPGR, NR3C2, NCOA2
Sitosterol- alpha1PGR, PTGS2, GABRA1, ADH1C , NR3C2
MandenolPTGS1, PTGS2, NCOA2
2-MonooleinNCOA2