Comparative Studies on a Standardized Subfraction of Red Onion Peel Ethanolic Extract (Plant Substance), Quercetin (Pure Compound), and Their Cell Mechanism and Metabolism on MDA-MB-231

Figure 6

Effect of F1 (50 μg/mL) and quercetin (60 μg/mL) on the mRNA gene expression of (a) CYP1A1, (b) CYP1B1, and (c) CYP2S1 in MDA-MB-231 cells. The mRNA expression was normalized to the expression of GAPDH in each sample. The bar chart represents the mean ± SD of two independent experiments with significant differences indicated as , <0.01, and <0.001, compared to the controls. One-way ANOVA and Dunnett’s multiple comparison test were used for the statistical analysis.

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