Pharmacological Mechanisms of Shangke Huangshui against Skin and Soft Tissue Infection

Figure 7

SK inhibited TLR2/MyD88/NF-κB signaling pathway in SSTIs. (a) Representative western blots showed the protein expression of TLR2, MyD88, TAK1, AP1, and NF-κB. (b, c) Effect of SK on the mRNA expression of TLR2, MyD88, IRAK1, TRAF6, TAK1, AP1, JNK, P38, NF-κB, and IL-8 by qPCR. Values are expressed as mean ± SD in each group.  < 0.05 and  < 0.01 versus Mod group.

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