Research Article

[Retracted] The Differences of Metabolites in Different Parts of the Brain Induced by Shuxuetong Injection against Cerebral Ischemia-Reperfusion and Its Corresponding Mechanism

Table 1

Differential metabolites of Model group, Sham group, and SXT-M group.

PartNo.Metabolite nameRetention time(min)Measured mean mass (Da)Chemical formulaNormalized abundance (×105)
ShamModelSXT-M

Cortex1Orthanilic acid0.85172.0213C6H7NO3S1.151.92▲▲▲1.62∗∗
2Glutamine0.87145.0610C5H10N2O321.5030.72▲▲▲24.54∗∗
3Humantenine17.73353.1976C21H26N2O34.933.17▲▲▲5.11∗∗∗
4Dodecylbenzenesulfonic acid24.89325.1818C18H30O3S53.4064.05▲▲▲51.95∗∗∗
5Dodecyl sulfate24.40265.1460C12H26O4S113.22129.05▲▲106.75∗∗∗
6Yohimbic acid25.14339.1974C20H24N2O342.1649.02▲▲▲40.19∗∗∗
7S-sulforaphene1.38174.0010C6H9NOS23.484.78▲▲4.00
83-Hydroxypropanoic acid1.3189.0240C3H6O3137.90171.41▲▲141.70∗∗
9Dihydroorotic acid0.28157.0108C5H6N2O43.263.543.06∗∗∗
10Glyceric acid0.76105.0166C3H6O42.492.692.39∗∗
11Embelin24.86293.1771C17H26O481.5693.37▲▲77.97∗∗∗
12Etidronate23.68204.9879C2H8O7P21.621.801.45∗∗∗
13Threonic acid23.14135.0102C4H8O51.451.59▲▲1.45∗∗

Hippocampus1Fumaric acid1.29115.0030C4H4O40.320.280.32
2Embelin13.24293.1733C17H26O412.016.18▲▲▲9.10∗∗∗
3Glutamic acid14.55146.0348C5H9NO45.403.69▲▲5.25∗∗
4Butylparaben12.04193.0854C11H14O33.262.04▲▲▲2.90∗∗∗
52,4-Dihydroxybenzophenone0.84213.0473C13H10O34.116.39▲▲▲5.01

The model group was compared with the sham group, , ▲▲, ▲▲▲. The SXT-M group was compared with the model group: , ∗∗, and ∗∗∗.