[Retracted] The Differences of Metabolites in Different Parts of the Brain Induced by Shuxuetong Injection against Cerebral Ischemia-Reperfusion and Its Corresponding Mechanism
Table 1
Differential metabolites of Model group, Sham group, and SXT-M group.
Part
No.
Metabolite name
Retention time(min)
Measured mean mass (Da)
Chemical formula
Normalized abundance (×105)
Sham
Model
SXT-M
Cortex
1
Orthanilic acid
0.85
172.0213
C6H7NO3S
1.15
1.92▲▲▲
1.62∗∗
2
Glutamine
0.87
145.0610
C5H10N2O3
21.50
30.72▲▲▲
24.54∗∗
3
Humantenine
17.73
353.1976
C21H26N2O3
4.93
3.17▲▲▲
5.11∗∗∗
4
Dodecylbenzenesulfonic acid
24.89
325.1818
C18H30O3S
53.40
64.05▲▲▲
51.95∗∗∗
5
Dodecyl sulfate
24.40
265.1460
C12H26O4S
113.22
129.05▲▲
106.75∗∗∗
6
Yohimbic acid
25.14
339.1974
C20H24N2O3
42.16
49.02▲▲▲
40.19∗∗∗
7
S-sulforaphene
1.38
174.0010
C6H9NOS2
3.48
4.78▲▲
4.00∗
8
3-Hydroxypropanoic acid
1.31
89.0240
C3H6O3
137.90
171.41▲▲
141.70∗∗
9
Dihydroorotic acid
0.28
157.0108
C5H6N2O4
3.26
3.54▲
3.06∗∗∗
10
Glyceric acid
0.76
105.0166
C3H6O4
2.49
2.69▲
2.39∗∗
11
Embelin
24.86
293.1771
C17H26O4
81.56
93.37▲▲
77.97∗∗∗
12
Etidronate
23.68
204.9879
C2H8O7P2
1.62
1.80▲
1.45∗∗∗
13
Threonic acid
23.14
135.0102
C4H8O5
1.45
1.59▲▲
1.45∗∗
Hippocampus
1
Fumaric acid
1.29
115.0030
C4H4O4
0.32
0.28▲
0.32∗
2
Embelin
13.24
293.1733
C17H26O4
12.01
6.18▲▲▲
9.10∗∗∗
3
Glutamic acid
14.55
146.0348
C5H9NO4
5.40
3.69▲▲
5.25∗∗
4
Butylparaben
12.04
193.0854
C11H14O3
3.26
2.04▲▲▲
2.90∗∗∗
5
2,4-Dihydroxybenzophenone
0.84
213.0473
C13H10O3
4.11
6.39▲▲▲
5.01∗
The model group was compared with the sham group, ▲,▲▲,▲▲▲. The SXT-M group was compared with the model group: ∗,∗∗, and ∗∗∗.