Research Article

Guanxinping Tablets Inhibit ET-1-Induced Proliferation and Migration of MOVAS by Suppressing Activated PI3K/Akt/NF-κB Signaling Cascade

Table 1

The topology parameters of key targets.

Key targetTarget nameBetweennessClosenessDegree

INSInsulin0.0747020.866197104
IL6Interleukin 60.0324310.83108198
AKT1Serine-threonine protein kinase 10.0318430.82550397
VEGFAVascular endothelial growth factor A0.0180290.79354891
TNFTumor necrosis factor0.0201980.78846290
TP53Tumor protein 530.0150120.76397585
EGFEpidermal growth factor0.0216430.75925984
JUNJun proto-oncogene0.0103760.75460183