Research Article
Guanxinping Tablets Inhibit ET-1-Induced Proliferation and Migration of MOVAS by Suppressing Activated PI3K/Akt/NF-κB Signaling Cascade
Table 1
The topology parameters of key targets.
| Key target | Target name | Betweenness | Closeness | Degree |
| INS | Insulin | 0.074702 | 0.866197 | 104 | IL6 | Interleukin 6 | 0.032431 | 0.831081 | 98 | AKT1 | Serine-threonine protein kinase 1 | 0.031843 | 0.825503 | 97 | VEGFA | Vascular endothelial growth factor A | 0.018029 | 0.793548 | 91 | TNF | Tumor necrosis factor | 0.020198 | 0.788462 | 90 | TP53 | Tumor protein 53 | 0.015012 | 0.763975 | 85 | EGF | Epidermal growth factor | 0.021643 | 0.759259 | 84 | JUN | Jun proto-oncogene | 0.010376 | 0.754601 | 83 |
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