Efficacy of Rytigynia senegalensis Blume on Free Radical Scavenging, Inhibition of α-Amylase and α-Glucosidase Activity, and Blood Glucose Level
Table 7
Hypoglycemic plus antihyperglycemic effect of RSE.
Groups
Blood glucose levels (mg/dL)
0 min
30 min
60 min
90 min (3 g/kg D-glucose)
120 min
150 min
180 min
Control
49.5 ± 4.1
52.5 ± 2,2
40.0 ± 1.4
66.2 ± 1.3
68.5 ± 1.6
55.7 ± 2.7
49.0 ± 3.0
Glibenclamide
51.2 ± 2.1
51.2 ± 1.8
25.5 ± 2.2
45.7 ± 4.5
33.7 ± 2.6
25.5 ± 1.2
23.0 ± 1.1
RSE 50 mg/kg
44.0 ± 2.7
52.5 ± 2.9
34.0 ± 1.2
60.0 ± 3.8
59.2 ± 1.2
45.0 ± 5.8
40.2 ± 2.9
RSE 100 mg/kg
47.5 ± 2.2
53.0 ± 2.7
32.0 ± 3.2
65.7 ± 6.6
59.2 ± 5.5
39.7 ± 1.8
32.7 ± 2.4
RSE 200 mg/kg
51.2 ± 2.1
61.5 ± 1.5
40.7 ± 3.2
72.5 ± 3.1
64.2 ± 5.8
41.7 ± 3.2
31.5 ± 0.3
Each result represents the mean ± standard derivation (n = 6). Data analysis was performed by two-way ANOVA followed by Bonferroni’s post hoc test. ;; compared with the control group. RSE: Rytigynia senegalensis extract.