Antidiarrheal and Antibacterial Activities of Calpurnia aurea: Benth Seed Different Extracts

Table 1

Effect of the aqueous and 80% methanol seed extracts of C. aurea on castor oil-induced diarrhea model in mice.

Groups	Onset of diarrhea	Total stool frequency in 4 hrs	Total weight of wet diarrhea	% Inhibition of total wet fecal output	Weight of watery content of wet stools	% Inhibition of watery content of wet stool
DW	79.83 ± 2.78	9.17 ± 1.11	1.29 ± 0.08	—	0.69 ± 0.11	—
L3	147.00 ± 2.89^a1	2.33 ± 0.21^a3	0.56 ± 0.09^a2	56.59%	0.14 ± 0.03^a1	79.71%
CAW60	151.67 ± 19.23^a2	3.17 ± 0.75^a3	0.82 ± 0.21	36.43%	0.38 ± 0.18	44.93%
CAW120	156.00 ± 22.27^a2	2.17 ± 0.54^a3	0.65 ± 0.17^a1	49.61%	0.24 ± 0.11	65.23%
CAW240	177.83 ± 7.67^a3	1.83 ± 0.31^a3	0.48 ± 0.07^a2	62.80%	0.11 ± 0.03^a2	84.06
CAM60	103.17 ± 10.08	2.5 ± 0.34^a3	0.81 ± 0.15^a1	37.21%	0.32 ± 0.13^a1	53.62%
CAM120	126.33 ± 20.73	1.67 ± 0.21^a3	0.54 ± 0.11^a3	58.14%	0.18 ± 0.05^a2	73.91%
CAM240	203.67 ± 20.77^a3	1.17 ± 0.17^a3	0.38 ± 0.05^a3	70.54%	0.11 ± 0.01^a3	84.06%

Values are expressed as mean ± S.E.M (n = 6), analysis was performed using one way ANOVA followed by Tuckey post hoc test. Comparison was made among different groups: ^acompared to control; , , . DW = distilled water, L = loperamide, CAW = C. aurea water extract, and CAM = C. aurea 80% methanol extract.