Antidiarrheal and Antibacterial Activities of Calpurnia aurea: Benth Seed Different Extracts

Table 2

Effects of the aqueous and 80% methanol seed extracts of C. aurea on castor oil-induced gastrointestinal transit in mice.

Group	Total length of small intestine (cm)	Distance moved by the charcoal meal (cm)	Peristalsis index (%)	%Inhibition
DW	56.00 ± 1.13	44.17 ± 1.33	79.00 ± 2.63	—
L3	53.83 ± 1.28	16.67 ± 1.33^a3c3	30.81 ± 1.96^a3c3	62.26%
CAW60	52.67 ± 0.88	30.67 ± 1.98a3b3^d3e3	58.29 ± 3.74^a3b3d3e3	30.22%
CAW120	51.50 ± 1.45	18.83 ± 2.34^a3c3	36.63 ± 4.52^a3c3	57.37%
CAW240	54.00 ± 1.32	16.17 ± 1.05^a3c3	29.82 ± 1.31^a3c3	63.39%
CAM60	52.00 ± 1.81	22.17 ± 2.73^a3	42.23 ± 3.93^a3e1	49.81%
CAM120	55.67 ± 1.17	18.83 ± 2.47^a3	34.03 ± 4.69^a3	57.37%
CAM240	59.83 ± 1.05	17.17 ± 1.45^a3	28.55 ± 2.08^a3c1	61.13%

Values are expressed as mean ± S.E.M (n = 6), analysis was performed using one way ANOVA followed by Tuckey post hoc test, comparison was made among different groups: ^acompared to control, ^b to standard drug, ^c to 60 mg/kg aqueous, ^d to 120 mg/kg aqueous, ^e to 240 mg/kg aqueous; , , . DW = distilled water, L = loperamide, CAW = C. aurea water extract, and CAM = C. aurea 80% methanol extract.